Journal: Cell reports
Article Title: JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome
doi: 10.1016/j.celrep.2020.108407
Figure Lengend Snippet: (A) Flow cytometry analysis of IFNAR1, IFNGR2, and IL10RB cell surface expression on CD45+ white blood cells (WBCs) from the Dp10, Dp16, and Dp17 mouse strains; n = 5–9 animals per genotype. Data are presented as ratios of the geometric mean fluorescence intensity (RFI) of each IFNR on WBCs relative to WT littermates. Example histograms are shown in the top right corner, with light gray representing an isotype control antibody, dark gray/black representing values for WT littermates, and green representing values for Dp16.
Article Snippet: Recombinant human anti-mouse IL10RB (clone REA856) conjugated to PE , Miltenyi Biotec , Cat# 130-114-688; RRID: AB_2726752.
Techniques: Flow Cytometry, Expressing, Fluorescence, Control